According to the official website of Migration office YIMER 157 , since November 9, 2015 two new branches have been started their work at Besiktas and Beylikduzu. From this date on randevu paperwork for Short term, Long term and Family type residence permits as a First application for listed below districts will be as follows:
At Besiktas Migration office branch : if you reside at Besiktas, Beyoglu or Sisli districts
Address: Gönenoğlu Sokak, No:10 Gayrettepe/ BEŞİKTAŞ (at the same building with Beşiktaş İlçe Gıda, Tarım ve Hayvancılık Müdürlüğü).
At Beylikduzu Nigration office branch: if you reside at BEYLİKDÜZÜ, BÜYÜKÇEKMECE, ESENYURT districts
Address: Yakuplu Mahallesi Hürriyet Bulvarı No:18 Hükümet Konağı. BEYLİKDÜZÜ (Beylikdüzü Hükümet Konağı)
If you reside at any other district of Istanbul, apply for Student or Refugee residence permits or apply by post for extension of existing ikamet, you will still need to go to the main Migration office at Vatan street.